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CNIH2 Antibody (N-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q6PI25
Clone Names 100111235
Additional Information
Gene ID 254263
Other Names Protein cornichon homolog 2, CNIH-2, Cornichon family AMPA receptor auxiliary protein 2, Cornichon-like protein, CNIH2, CNIL
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CNIH2
Synonyms CNIL
Function Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by regulating their rates of activation, deactivation and desensitization. Blocks CACNG8-mediated resensitization of AMPA receptors.
Cellular Location Endoplasmic reticulum membrane; Multi-pass membrane protein. Postsynaptic cell membrane; Multi-pass membrane protein. Cell projection, dendrite. Cell projection, dendritic spine. Postsynaptic density. Note=Also localizes to the cell membrane of extrasynaptic sites (dendritic shafts, spines of pyramidal cells).
Tissue Location Expression is up-regulated in dorsolateral prefrontal cortex of patients with schizophrenia (postmortem brain study).
Research Areas
Citations (0)
citation

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Background

Involved in the transport and maturation of proteins (By similarity).

References

Hoshino, H., et al. Mol. Biol. Cell 18(4):1143-1152(2007)Lamesch, P., et al. Genomics 89(3):307-315(2007)

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$ 277.78
Cat# BP11529a
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