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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   OCT3/4 Antibody (C279) Blocking peptide   

OCT3/4 Antibody (C279) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q01860
Clone Names 71130128
Peptide ID 71130128
Additional Information
Gene ID 5460
Other Names POU domain, class 5, transcription factor 1, Octamer-binding protein 3, Oct-3, Octamer-binding protein 4, Oct-4, Octamer-binding transcription factor 3, OTF-3, POU5F1, OCT3, OCT4, OTF3
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name POU5F1
Synonyms OCT3, OCT4, OTF3
Function Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency.
Cellular Location Cytoplasm. Nucleus. Note=Expressed in a diffuse and slightly punctuate pattern
Tissue Location Expressed in developing brain. Highest levels found in specific cell layers of the cortex, the olfactory bulb, the hippocampus and the cerebellum. Low levels of expression in adult tissues.
Research Areas
Citations (0)

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This gene encodes a transcription factor containing a POUhomeodomain. This transcription factor plays a role in embryonicdevelopment, especially during early embryogenesis, and it isnecessary for embryonic stem cell pluripotency. A translocation ofthis gene with the Ewing's sarcoma gene, t(6;22)(p21;q12), has beenlinked to tumor formation. Alternative splicing, as well as usageof alternative translation initiation codons, results in multipleisoforms, one of which initiates at a non-AUG (CUG) start codon.Related pseudogenes have been identified on chromosomes 1, 3, 8,10, and 12.


Abu-Remaileh, M., et al. EMBO J. 29(19):3236-3248(2010)Ucisik-Akkaya, E., et al. Mol. Hum. Reprod. 16(10):770-777(2010)Schultz, S.S., et al. Mol. Cell. Biol. 30(18):4521-4534(2010)Kim, S., et al. Br. J. Cancer 102(2):436-446(2010)Wang, X., et al. Stem Cells 27(6):1265-1275(2009)

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$ 80.00
Cat# BP11546a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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