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F11 Antibody (Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession P03951
Clone Names 80513119
Peptide ID 80513119
Additional Information
Gene ID 2160
Other Names Coagulation factor XI, FXI, Plasma thromboplastin antecedent, PTA, Coagulation factor XIa heavy chain, Coagulation factor XIa light chain, F11
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name F11
Function Factor XI triggers the middle phase of the intrinsic pathway of blood coagulation by activating factor IX.
Cellular Location Secreted.
Tissue Location Isoform 2 is produced by platelets and megakaryocytes but absent from other blood cells
Research Areas
Citations (0)

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This gene encodes coagulation factor XI of the bloodcoagulation cascade. This protein is present in plasma as azymogen, which is a unique plasma coagulation enzyme because itexists as a homodimer consisting of two identical polypeptidechains linked by disulfide bonds. During activation of the plasmafactor XI, an internal peptide bond is cleaved by factor XIIa (orXII) in each of the two chains, resulting in activated factor XIa,a serine protease composed of two heavy and two light chains heldtogether by disulfide bonds. This activated plasma factor XItriggers the middle phase of the intrisic pathway of bloodcoagulation by activating factor IX. Defects in this factor lead toRosenthal syndrome, a blood coagulation abnormality. [provided byRefSeq].


Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Wong, P.C., et al. Thromb. Haemost. 104(2):302-310(2010)Whelihan, M.F., et al. J. Thromb. Haemost. 8(7):1532-1539(2010)Delluc, A., et al. Thromb. Haemost. 103(6):1161-1169(2010)Barber, M.J., et al. PLoS ONE 5 (3), E9763 (2010) :

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$ 80.00
Cat# BP11568c
Availability: In Stock
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