|Other Names||Retinal guanylyl cyclase 1, RETGC-1, Guanylate cyclase 2D, retinal, Rod outer segment membrane guanylate cyclase, ROS-GC, GUCY2D, CORD6, GUC1A4, GUC2D, RETGC, RETGC1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Synonyms||CORD6, GUC1A4, GUC2D, RETGC, RETGC1|
|Function||Probably plays a specific functional role in the rods and/or cones of photoreceptors. It may be the enzyme involved in the resynthesis of cGMP required for recovery of the dark state after phototransduction.|
|Cellular Location||Membrane; Single-pass type I membrane protein|
|Tissue Location||Retina. Localized exclusively in the nuclei and inner segments of the rod and cone photoreceptor cells|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
This gene encodes a retina-specific guanylate cyclase,which is a member of the membrane guanylyl cyclase family. Likeother membrane guanylyl cyclases, this enzyme has a hydrophobicamino-terminal signal sequence followed by a large extracellulardomain, a single membrane spanning domain, a kinase homologydomain, and a guanylyl cyclase catalytic domain. In contrast toother membrane guanylyl cyclases, this enzyme is not activated bynatriuretic peptides. Mutations in this gene result in Lebercongenital amaurosis and cone-rod dystrophy-6 diseases. [providedby RefSeq].
Silva, L.K., et al. Eur. J. Hum. Genet. 18(11):1221-1227(2010)Liu, C.Y., et al. Carcinogenesis 31(7):1259-1263(2010)Joslyn, G., et al. Alcohol. Clin. Exp. Res. 34(5):800-812(2010)Pasadhika, S., et al. Invest. Ophthalmol. Vis. Sci. 51(5):2608-2614(2010)Sundaresan, P., et al. Mol. Vis. 15, 1781-1787 (2009) :
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.