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CTND1 Antibody (Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession O60716
Clone Names 80808085
Peptide ID 80808085
Additional Information
Gene ID 1500
Other Names Catenin delta-1, Cadherin-associated Src substrate, CAS, p120 catenin, p120(ctn), p120(cas), CTNND1, KIAA0384
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms KIAA0384
Function Binds to and inhibits the transcriptional repressor ZBTB33, which may lead to activation of target genes of the Wnt signaling pathway (By similarity). Associates with and regulates the cell adhesion properties of both C-, E- and N-cadherins, being critical for their surface stability. Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. Promotes GLIS2 C-terminal cleavage.
Cellular Location Cytoplasm. Nucleus. Cell membrane. Note=Interaction with GLIS2 promotes nuclear translocation (By similarity). Detected at cell-cell contacts. NANOS1 induces its translocation from sites of cell-cell contact to the cytoplasm Isoforms 4A and 1AB are excluded from the nucleus. Isoform 2A: Nucleus.
Tissue Location Expressed in vascular endothelium. Melanocytes and melanoma cells primarily express the long isoform 1A, whereas keratinocytes express shorter isoforms, especially 3A. The shortest isoform 4A, is detected in normal keratinocytes and melanocytes, and generally lost from cells derived from squamous cell carcinomas or melanomas. The C-terminal alternatively spliced exon B is present in the p120ctn transcripts in the colon, intestine and prostate, but lost in several tumor tissues derived from these organs.
Research Areas
Citations (0)

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This gene encodes a member of the Armadillo proteinfamily, which function in adhesion between cells and signaltransduction. Multiple translation initiation codons andalthernative splicing result in many different isoforms beingtranslated. Not all of the full-length natures of the describedtranscript variants have been determined.


Zhang, J., et al. Microvasc. Res. 80(2):233-239(2010)Wong, L.E., et al. J. Cell. Biochem. 110(5):1244-1254(2010)Sakamoto, N., et al. Biochem. Biophys. Res. Commun. 398(3):426-432(2010)Mortazavi, F., et al. Mol. Cancer Res. 8(5):762-774(2010)Kumper, S., et al. PLoS ONE 5 (7), E11801 (2010) :

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$ 80.00
Cat# BP11572c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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