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SFRP4 Antibody (C-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q6FHJ7
Clone Names 80924199
Peptide ID 80924199
Additional Information
Gene ID 6424
Other Names Secreted frizzled-related protein 4, sFRP-4, Frizzled protein, human endometrium, FrpHE, SFRP4, FRPHE
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SFRP4
Synonyms FRPHE
Function Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP4 may act as a regulator of adult uterine morphology and function. Increases apoptosis during ovulation possibly through modulation of FZ1/FZ4/WNT4 signaling (By similarity). Has phosphaturic effects by specifically inhibiting sodium-dependent phosphate uptake.
Cellular Location Secreted. Note=Cytoplasmic in ovarian tumor cells
Tissue Location Expressed in mesenchymal cells. Highly expressed in the stroma of proliferative endometrium. Expressed in cardiomyocytes. Shows moderate to strong expression in ovarian tumors with expression increasing as the tumor stage increases. In ovarian tumors, expression levels are inversely correlated with expression of CTNNB1 (at protein level)
Research Areas
Citations (0)

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Secreted frizzled-related protein 4 (SFRP4) is a member ofthe SFRP family that contains a cysteine-rich domain homologous tothe putative Wnt-binding site of Frizzled proteins. SFRPs act assoluble modulators of Wnt signaling. The expression of SFRP4 inventricular myocardium correlates with apoptosis related geneexpression.


Lee, D.Y., et al. Menopause 17(5):1064-1070(2010)Kohno, H., et al. Oncol. Rep. 24(2):423-431(2010)Frank, B., et al. Carcinogenesis 31(8):1381-1386(2010)Huang, D., et al. J. Cancer Res. Clin. Oncol. 136(3):395-401(2010)Hirata, H., et al. Cancer 115(19):4488-4503(2009)

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$ 80.00
Cat# BP11574b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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