|Other Names||Transcription factor 21, TCF-21, Capsulin, Class A basic helix-loop-helix protein 23, bHLHa23, Epicardin, Podocyte-expressed 1, Pod-1, TCF21, BHLHA23, POD1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Involved in epithelial-mesenchymal interactions in kidney and lung morphogenesis that include epithelial differentiation and branching morphogenesis. May play a role in the specification or differentiation of one or more subsets of epicardial cell types.|
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Provided below are standard protocols that you may find useful for product applications.
TCF21 encodes a transcription factor of the basichelix-loop-helix family. The TCF21 product is mesoderm specific,and expressed in embryonic epicardium, mesenchyme-derived tissuesof lung, gut, gonad, and both mesenchymal and glomerular epithelialcells in the kidney. Two transcript variants encoding the sameprotein have been found for this gene.
Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :Vieira, A.R., et al. Genet. Med. 10(9):668-674(2008)Melzer, D., et al. PLoS Genet. 4 (5), E1000072 (2008) :Smith, L.T., et al. Proc. Natl. Acad. Sci. U.S.A. 103(4):982-987(2006)Colland, F., et al. Genome Res. 14(7):1324-1332(2004)
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