Register or Login
All
  • All
  • Uniprot Id
  • Catalog #
  • Peptide Sequence
>   home   >   Products   >   Peptides   >   Blocking Peptides   >   HCFC1R1 Antibody (N-term) Blocking peptide   

HCFC1R1 Antibody (N-term) Blocking peptide

Synthetic peptide

     
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Primary Accession Q9NWW0
Clone Names 100126135
Peptide ID 100126135
Additional Information
Other Names Host cell factor C1 regulator 1, HCF-1 beta-propeller-interacting protein, HCFC1R1, HPIP
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name HCFC1R1
Synonyms HPIP
Function Regulates HCFC1 activity by modulating its subcellular localization. Overexpression of HCFC1R1 leads to accumulation of HCFC1 in the cytoplasm. HCFC1R1-mediated export may provide the pool of cytoplasmic HCFC1 required for import of virion-derived VP16 into the nucleus.
Cellular Location Cytoplasm. Nucleus. Note=Shuttles between the nucleus and cytoplasm in a CRM1-dependent manner
Tissue Location Widely expressed. EMBL; AY116892; AAM49798.1; -; mRNA EMBL; AK000575; BAA91265.1; -; mRNA EMBL; CR457245; CAG33526.1; -; mRNA EMBL; CH471112; EAW85425.1; -; Genomic_DNA EMBL; CH471112; EAW85426.1; -; Genomic_DNA EMBL; BC064026; AAH64026.1; -; mRNA EMBL; BC080178; AAH80178.1; -; mRNA CCDS; CCDS10490.1; -. [Q9NWW0-1] CCDS; CCDS32375.1; -. [Q9NWW0-2] RefSeq; NP_001002017.1; NM_001002017.2. [Q9NWW0-2] RefSeq; NP_001002018.1; NM_001002018.2. [Q9NWW0-1] RefSeq; NP_001275594.1; NM_001288665.1. [Q9NWW0-1] RefSeq; NP_001275595.1; NM_001288666.1. [Q9NWW0-2] RefSeq; NP_001275596.1; NM_001288667.1 RefSeq; NP_001275597.1; NM_001288668.1 RefSeq; NP_060355.1; NM_017885.3. [Q9NWW0-1] UniGene; Hs.423103; - ProteinModelPortal; Q9NWW0; - BioGrid; 120320; 3 IntAct; Q9NWW0; 1 MINT; MINT-1424323; - iPTMnet; Q9NWW0; - PhosphoSitePlus; Q9NWW0; - BioMuta; HCFC1R1; - PaxDb; Q9NWW0; - PRIDE; Q9NWW0; - DNASU; 54985; - Ensembl; ENST00000248089; ENSP00000248089; ENSG00000103145. [Q9NWW0-1] Ensembl; ENST00000574151; ENSP00000459178; ENSG00000103145. [Q9NWW0-2] Ensembl; ENST00000574980; ENSP00000460639; ENSG00000103145. [Q9NWW0-1] GeneID; 54985; - KEGG; hsa:54985; - UCSC; uc002csy.3; human. [Q9NWW0-1] CTD; 54985; - GeneCards; HCFC1R1; - HGNC; HGNC:21198; HCFC1R1 HPA; HPA059647; - neXtProt; NX_Q9NWW0; - OpenTargets; ENSG00000103145; - PharmGKB; PA134951485; - eggNOG; ENOG410IZTH; Eukaryota eggNOG; ENOG4111EF3; LUCA GeneTree; ENSGT00390000015785; - HOGENOM; HOG000112942; - HOVERGEN; HBG107981; - InParanoid; Q9NWW0; - OrthoDB; EOG091G0VZ8; - PhylomeDB; Q9NWW0; - TreeFam; TF338381; - BioCyc; ZFISH:ENSG00000103145-MONOMER; - ChiTaRS; HCFC1R1; human GenomeRNAi; 54985; - PRO; PR:Q9NWW0; - Proteomes; UP000005640; Chromosome 16 Bgee; ENSG00000103145; - CleanEx; HS_HCFC1R1; - ExpressionAtlas; Q9NWW0; baseline and differential Genevisible; Q9NWW0; HS GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell InterPro; IPR029195; HCFC1R1 Pfam; PF15226; HPIP; 1 1: Evidence at protein level; Alternative splicing; Complete proteome; Cytoplasm; Nucleus; Polymorphism; Reference proteome CHAIN 1 138 Host cell factor C1 regulator 1 /FTId=PRO_0000338978 REGION 76 79 Interaction with HCFC1 MOTIF 110 119 Nuclear export signal VAR_SEQ 32 51 SSPLRGAVPMSTKRRLEEEQ -> R (in isoform 2) /FTId=VSP_034082 VARIANT 92 92 P -> Q (in dbSNP:rs10508) /FTId=VAR_043849 MUTAGEN 76 79 DHPY->AAPA: Loss of interaction with HCFC1. MUTAGEN 117 119 LRL->ARA: Reduces nuclear export SEQUENCE 138 AA; 15291 MW; 34A9A04735276A16 CRC64; MILQQPLQRG PQGGAQRLPR AALGVTWGLD ASSPLRGAVP MSTKRRLEEE QEPLRKQFLS EENMATHFSQ LSLHNDHPYC SPPMTFSPAL PPLRSPCSEL LLWRYPGSLI PEALRLLRLG DTPSPPYPAT PAGDIMEL
Research Areas
Citations (0)

Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.

Submit your citation using an Abgent antibody to
info@abgent.com, and receive a free "I Love Antibodies" mug.

Background

Regulates HCFC1 activity by modulating its subcellular localization. Overexpression of HCFC1R1 leads to accumulation of HCFC1 in the cytoplasm. HCFC1R1-mediated export may provide the pool of cytoplasmic HCFC1 required for import of virion-derived VP16 into the nucleus.

References

Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Lamesch, P., et al. Genomics 89(3):307-315(2007)Mahajan, S.S., et al. J. Biol. Chem. 277(46):44292-44299(2002)

FeedBack
Abgent welcomes feedback from its customers.

If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.

If you have any additional inquiries please email technical services at tech@abgent.com.

$ 80.00
Cat# BP11644a
Size:
Quantity:
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
Request Quote Here

Ordering Information

United States
AlbaniaAustraliaAustriaBelgiumBosnia & HerzegovinaBrazilBulgariaCanadaChinaCroatiaCyprusCzech RepublicDenmarkEstoniaFinlandFranceGermanyGreeceHong KongHungaryIcelandIndiaIndonesiaIrelandIsraelItalyJapanKoreaLatviaLithuaniaLuxembourgMacedoniaMalaysiaMaltaNetherlandsNew ZealandNorwayPakistanPolandPortugalRomaniaSerbiaSingaporeSlovakiaSloveniaSouth AfricaSpainSwedenSwitzerlandTaiwanTurkeyUnited KingdomUnited StatesVietnamOthers
Abgent, Inc.
(888) 735-7227 / (858) 622-0099
(858) 622-0609
USA Headquarters
(888) 735-7227 / (858) 622-0099 or (858) 875-1900

Shipping Information

Domestic orders (in stock items)
Shipped out the same day. Orders placed after 1 PM (PST) will ship out the next business day.
International orders
Contact your local distributors
Crown Flash17-30% Off
Terms & Conditions