|Other Names||Monocarboxylate transporter 3, MCT 3, Solute carrier family 16 member 8, SLC16A8, MCT3|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate (By similarity).|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
|Tissue Location||Retinal pigment epithelium.|
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Provided below are standard protocols that you may find useful for product applications.
SLC16A8 is a member of a family of proton-coupledmonocarboxylate transporters that mediate lactate transport acrosscell membranes (Yoon et al., 1999 [PubMed 10493836]).[supplied byOMIM].
Yokoyama, K., et al. Nephron Clin Pract 115 (4), C237-C243 (2010) :Wilson, M.C., et al. J. Biol. Chem. 280(29):27213-27221(2005)Halestrap, A.P., et al. Pflugers Arch. 447(5):619-628(2004)Philp, N.J., et al. Invest. Ophthalmol. Vis. Sci. 44(4):1716-1721(2003)Dunham, I., et al. Nature 402(6761):489-495(1999)
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