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SLC16A8 Antibody (C-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession O95907
Clone Names 101008287
Additional Information
Gene ID 23539
Other Names Monocarboxylate transporter 3, MCT 3, Solute carrier family 16 member 8, SLC16A8, MCT3
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SLC16A8 (HGNC:16270)
Synonyms MCT3
Function Probable retinal pigment epithelium (RPE)-specific proton- coupled L-lactate transporter (By similarity). May facilitate transport of lactate and H(+) out of the retina and could therefore play a role in pH and ion homeostasis of the outer retina (By similarity).
Cellular Location Basolateral cell membrane; Multi-pass membrane protein. Note=Basolateral sorting signals (BLSS) in C-terminal cytoplasmic tail ensure its basolateral expression (PubMed:21199217) Colocalizes with BSG in basolateral cell membrane of the retinal pigment epithelium (By similarity). {ECO:0000250|UniProtKB:O35308, ECO:0000269|PubMed:21199217}
Tissue Location Retinal pigment epithelium.
Research Areas
Citations (0)
citation

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Background

SLC16A8 is a member of a family of proton-coupledmonocarboxylate transporters that mediate lactate transport acrosscell membranes (Yoon et al., 1999 [PubMed 10493836]).[supplied byOMIM].

References

Yokoyama, K., et al. Nephron Clin Pract 115 (4), C237-C243 (2010) :Wilson, M.C., et al. J. Biol. Chem. 280(29):27213-27221(2005)Halestrap, A.P., et al. Pflugers Arch. 447(5):619-628(2004)Philp, N.J., et al. Invest. Ophthalmol. Vis. Sci. 44(4):1716-1721(2003)Dunham, I., et al. Nature 402(6761):489-495(1999)

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$ 277.78
Cat# BP11651b
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