SLC16A8 Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | O95907 |
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Clone Names | 101008287 |
Gene ID | 23539 |
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Other Names | Monocarboxylate transporter 3, MCT 3, Solute carrier family 16 member 8, SLC16A8, MCT3 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | SLC16A8 (HGNC:16270) |
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Synonyms | MCT3 |
Function | Probable retinal pigment epithelium (RPE)-specific proton- coupled L-lactate transporter (By similarity). May facilitate transport of lactate and H(+) out of the retina and could therefore play a role in pH and ion homeostasis of the outer retina (By similarity). |
Cellular Location | Basolateral cell membrane; Multi-pass membrane protein. Note=Basolateral sorting signals (BLSS) in C-terminal cytoplasmic tail ensure its basolateral expression (PubMed:21199217) Colocalizes with BSG in basolateral cell membrane of the retinal pigment epithelium (By similarity). {ECO:0000250|UniProtKB:O35308, ECO:0000269|PubMed:21199217} |
Tissue Location | Retinal pigment epithelium. |
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Provided below are standard protocols that you may find useful for product applications.
Background
SLC16A8 is a member of a family of proton-coupledmonocarboxylate transporters that mediate lactate transport acrosscell membranes (Yoon et al., 1999 [PubMed 10493836]).[supplied byOMIM].
References
Yokoyama, K., et al. Nephron Clin Pract 115 (4), C237-C243 (2010) :Wilson, M.C., et al. J. Biol. Chem. 280(29):27213-27221(2005)Halestrap, A.P., et al. Pflugers Arch. 447(5):619-628(2004)Philp, N.J., et al. Invest. Ophthalmol. Vis. Sci. 44(4):1716-1721(2003)Dunham, I., et al. Nature 402(6761):489-495(1999)
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