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OGN Antibody (C-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession P20774
Clone Names 71211149
Additional Information
Gene ID 4969
Other Names Mimecan, Osteoglycin, Osteoinductive factor, OIF, OGN, OIF, SLRR3A
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name OGN
Synonyms OIF, SLRR3A
Function Induces bone formation in conjunction with TGF-beta-1 or TGF- beta-2.
Cellular Location Secreted, extracellular space, extracellular matrix {ECO:0000250|UniProtKB:Q8MJF1}
Tissue Location Bone.
Research Areas
Citations (0)
citation

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Background

The hepatotrophic factor designated augmenter of liverregeneration (ALR) is thought to be one of the factors responsiblefor the extraordinary regenerative capacity of mammalian liver. Ithas also been called hepatic regenerative stimulation substance(HSS). The gene resides on chromosome 16 in the interval containingthe locus for polycystic kidney disease (PKD1). The putative geneproduct is 42% similar to the scERV1 protein of yeast. The yeastscERV1 gene had been found to be essential for oxidativephosphorylation, the maintenance of mitochondrial genomes, and thecell division cycle. The human gene is both the structural andfunctional homolog of the yeast scERV1 gene.

References

Dong, L.Y., et al. Biochem. J. 431(2):277-287(2010)Li, W., et al. FEBS Lett. 584(18):3929-3935(2010)Daithankar, V.N., et al. Biochemistry 49(31):6737-6745(2010)Dayoub, R., et al. Biochem. Biophys. Res. Commun. 395(4):465-470(2010)Chang, J., et al. World J. Gastroenterol. 16(2):193-200(2010)

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$ 277.78
Cat# BP11671b
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