OGN Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | P20774 |
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Clone Names | 71211149 |
Gene ID | 4969 |
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Other Names | Mimecan, Osteoglycin, Osteoinductive factor, OIF, OGN, OIF, SLRR3A |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | OGN |
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Synonyms | OIF, SLRR3A |
Function | Induces bone formation in conjunction with TGF-beta-1 or TGF- beta-2. |
Cellular Location | Secreted, extracellular space, extracellular matrix {ECO:0000250|UniProtKB:Q8MJF1} |
Tissue Location | Bone. |
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Provided below are standard protocols that you may find useful for product applications.
Background
The hepatotrophic factor designated augmenter of liverregeneration (ALR) is thought to be one of the factors responsiblefor the extraordinary regenerative capacity of mammalian liver. Ithas also been called hepatic regenerative stimulation substance(HSS). The gene resides on chromosome 16 in the interval containingthe locus for polycystic kidney disease (PKD1). The putative geneproduct is 42% similar to the scERV1 protein of yeast. The yeastscERV1 gene had been found to be essential for oxidativephosphorylation, the maintenance of mitochondrial genomes, and thecell division cycle. The human gene is both the structural andfunctional homolog of the yeast scERV1 gene.
References
Dong, L.Y., et al. Biochem. J. 431(2):277-287(2010)Li, W., et al. FEBS Lett. 584(18):3929-3935(2010)Daithankar, V.N., et al. Biochemistry 49(31):6737-6745(2010)Dayoub, R., et al. Biochem. Biophys. Res. Commun. 395(4):465-470(2010)Chang, J., et al. World J. Gastroenterol. 16(2):193-200(2010)
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