Foundational characteristics of cancer include proliferation, angiogenesis, migration, evasion of apoptosis, and cellular immortality. Find key markers for these cellular processes and antibodies to detect them.
The SUMOplot™ Analysis Program predicts and scores sumoylation sites in your protein. SUMOylation is a post-translational modification involved in various cellular processes, such as nuclear-cytosolic transport, transcriptional regulation, apoptosis, protein stability, response to stress, and progression through the cell cycle.
The Autophagy Receptor Motif Plotter predicts and scores autophagy receptor binding sites in your protein. Identifying proteins connected to this pathway is critical to understanding the role of autophagy in physiological as well as pathological processes such as development, differentiation, neurodegenerative diseases, stress, infection, and cancer.
OC90 Antibody (Center) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q02509 |
|---|---|
| Clone Names | 71130119 |
| Gene ID | 729330 |
|---|---|
| Other Names | Otoconin-90, Oc90, Phospholipase A2 homolog, OC90, PLA2L |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | OC90 (HGNC:8100) |
|---|---|
| Synonyms | PLA2L |
| Function | Major protein of the otoconia, a calcium carbonate structure in the saccule and utricle of the ear. Together with OTOL1, acts as a scaffold for otoconia biomineralization: sequesters calcium and forms interconnecting fibrils between otoconia that are incorporated into the calcium crystal structure. Together with OTOL1, modulates calcite crystal morphology and growth kinetics. It is unlikely that this protein has phospholipase A2 activity. |
| Cellular Location | Secreted {ECO:0000250|UniProtKB:P81869}. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Nucleolin (NCL), a eukaryotic nucleolar phosphoprotein, isinvolved in the synthesis and maturation of ribosomes. It islocated mainly in dense fibrillar regions of the nucleolus. HumanNCL gene consists of 14 exons with 13 introns and spansapproximately 11kb. The intron 11 of the NCL gene encodes a smallnucleolar RNA, termed U20.
References
Ishimaru, D., et al. J. Biol. Chem. 285(35):27182-27191(2010)Tulchin, N., et al. Am. J. Pathol. 176(3):1203-1214(2010)Strang, B.L., et al. J. Virol. 84(4):1771-1784(2010)Bertrand, L., et al. J. Virol. 84(1):109-118(2010)Jerke, U., et al. PLoS ONE 4 (12), E8302 (2009) :
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.
Ordering Information
Shipping Information
