LSM7 Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9UK45 |
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Clone Names | 80522050 |
Gene ID | 51690 |
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Other Names | U6 snRNA-associated Sm-like protein LSm7, LSM7 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | LSM7 |
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Function | Plays a role in pre-mRNA splicing as component of the U4/U6- U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex) (PubMed:28781166). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA (PubMed:10523320). |
Cellular Location | Nucleus |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the bicoid sub-family ofhomeodomain-containing transcription factors. The encoded proteinacts as a transcription factor and may play a role in brain andsensory organ development. A similar protein in mice is requiredfor proper forebrain development. Two transcript variants encodingdistinct isoforms have been identified for this gene. Otheralternative splice variants may exist, but their full lengthsequences have not been determined.
References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Masuda, T., et al. J. Biol. Chem. 285(35):26933-26944(2010)Gonzalez-Rodriguez, J., et al. Br J Ophthalmol 94(8):1100-1104(2010)Chung, C.Y., et al. Brain 133 (PT 7), 2022-2031 (2010) :Ashkenazi-Hoffnung, L., et al. Hum. Genet. 127(6):721-729(2010)
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