|Other Names||U6 snRNA-associated Sm-like protein LSm7, LSM7|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Binds specifically to the 3'-terminal U-tract of U6 snRNA and is probably a component of the spliceosome.|
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This gene encodes a member of the bicoid sub-family ofhomeodomain-containing transcription factors. The encoded proteinacts as a transcription factor and may play a role in brain andsensory organ development. A similar protein in mice is requiredfor proper forebrain development. Two transcript variants encodingdistinct isoforms have been identified for this gene. Otheralternative splice variants may exist, but their full lengthsequences have not been determined.
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Masuda, T., et al. J. Biol. Chem. 285(35):26933-26944(2010)Gonzalez-Rodriguez, J., et al. Br J Ophthalmol 94(8):1100-1104(2010)Chung, C.Y., et al. Brain 133 (PT 7), 2022-2031 (2010) :Ashkenazi-Hoffnung, L., et al. Hum. Genet. 127(6):721-729(2010)
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