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ITIH1 Antibody (Center) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P19827 |
|---|---|
| Clone Names | 80917028 |
| Gene ID | 3697 |
|---|---|
| Other Names | Inter-alpha-trypsin inhibitor heavy chain H1, ITI heavy chain H1, ITI-HC1, Inter-alpha-inhibitor heavy chain 1, Inter-alpha-trypsin inhibitor complex component III, Serum-derived hyaluronan-associated protein, SHAP, ITIH1, IGHEP1 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | ITIH1 |
|---|---|
| Synonyms | IGHEP1 |
| Function | May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes. |
| Cellular Location | Secreted. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene is a member of the type IV, cyclic AMP(cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family.Cyclic nucleotides are important second messengers that regulateand mediate a number of cellular responses to extracellularsignals, such as hormones, light, and neurotransmitters. The cyclicnucleotide phosphodiesterases (PDEs) regulate the cellularconcentrations of cyclic nucleotides and thereby play a role insignal transduction. This gene encodes a protein that specificallyhydrolyzes cAMP. Altered activity of this protein has beenassociated with schizophrenia and bipolar affective disorder.Alternate transcriptional splice variants, encoding differentisoforms, have been characterized.
References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Souza, R.P., et al. Int Clin Psychopharmacol 25(5):264-269(2010)Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Joslyn, G., et al. Alcohol. Clin. Exp. Res. 34(5):800-812(2010)Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
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