|Other Names||Glutamate dehydrogenase 1, mitochondrial, GDH 1, GLUD1, GLUD|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Mitochondrial glutamate dehydrogenase that converts L- glutamate into alpha-ketoglutarate. Plays a key role in glutamine anaplerosis by producing alpha-ketoglutarate, an important intermediate in the tricarboxylic acid cycle. May be involved in learning and memory reactions by increasing the turnover of the excitatory neurotransmitter glutamate (By similarity).|
|Cellular Location||Mitochondrion matrix.|
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Provided below are standard protocols that you may find useful for product applications.
The PAX genes, including PAX1, are a highly conservedfamily of developmental control genes that encode transcriptionfactors and have been shown to play a role in pattern formationduring embryogenesis in vertebrates (McGaughran et al., 2003[PubMed 12774041]). See PAX7 (MIM 167410) for a discussion ofpaired box domain genes.
Huang, T.H., et al. Int. J. Gynecol. Cancer 20(4):513-519(2010)Yerges, L.M., et al. J. Bone Miner. Res. 24(12):2039-2049(2009)Hillmer, A.M., et al. Nat. Genet. 40(11):1279-1281(2008)Richards, J.B., et al. Nat. Genet. 40(11):1282-1284(2008)Fei, Q., et al. Zhonghua Yi Xue Za Zhi 88(37):2597-2602(2008)
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