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GLUD1 Antibody (C-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession P00367
Clone Names 81020127
Additional Information
Gene ID 2746
Other Names Glutamate dehydrogenase 1, mitochondrial, GDH 1, GLUD1, GLUD
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name GLUD1
Synonyms GLUD
Function Mitochondrial glutamate dehydrogenase that catalyzes the conversion of L-glutamate into alpha-ketoglutarate. Plays a key role in glutamine anaplerosis by producing alpha-ketoglutarate, an important intermediate in the tricarboxylic acid cycle (PubMed:11032875, PubMed:16959573, PubMed:11254391, PubMed:16023112). Plays a role in insulin homeostasis (PubMed:9571255, PubMed:11297618). May be involved in learning and memory reactions by increasing the turnover of the excitatory neurotransmitter glutamate (By similarity).
Cellular Location Mitochondrion. Endoplasmic reticulum. Note=Mostly translocates into the mitochondria, only a small amount of the protein localizes to the endoplasmic reticulum.
Research Areas
Citations (0)
citation

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Background

The PAX genes, including PAX1, are a highly conservedfamily of developmental control genes that encode transcriptionfactors and have been shown to play a role in pattern formationduring embryogenesis in vertebrates (McGaughran et al., 2003[PubMed 12774041]). See PAX7 (MIM 167410) for a discussion ofpaired box domain genes.

References

Huang, T.H., et al. Int. J. Gynecol. Cancer 20(4):513-519(2010)Yerges, L.M., et al. J. Bone Miner. Res. 24(12):2039-2049(2009)Hillmer, A.M., et al. Nat. Genet. 40(11):1279-1281(2008)Richards, J.B., et al. Nat. Genet. 40(11):1282-1284(2008)Fei, Q., et al. Zhonghua Yi Xue Za Zhi 88(37):2597-2602(2008)

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$ 277.78
Cat# BP11701b
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