|Other Names||Transcription factor jun-B, JUNB|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Transcription factor involved in regulating gene activity following the primary growth factor response. Binds to the DNA sequence 5'-TGA[CG]TCA-3'.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a transcription factor that is a memberof the leucine zipper family of DNA binding proteins. This proteinbinds as a homodimer to the cAMP-responsive element, an octamericpalindrome. The protein is phosphorylated by several proteinkinases, and induces transcription of genes in response to hormonalstimulation of the cAMP pathway. Alternate splicing of this generesults in two transcript variants encoding different isoforms.
Jablonski, K.A., et al. Diabetes 59(10):2672-2681(2010)Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Chen, G., et al. J. Neurosci. 30(39):13066-13077(2010)Serretti, A., et al. J Affect Disord (2010) In press :Melnikova, V.O., et al. PLoS ONE 5 (8), E12452 (2010) :
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