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JUNB Antibody (Center) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession P17275
Clone Names 81202057
Peptide ID 81202057
Additional Information
Gene ID 3726
Other Names Transcription factor jun-B, JUNB
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name JUNB
Function Transcription factor involved in regulating gene activity following the primary growth factor response. Binds to the DNA sequence 5'-TGA[CG]TCA-3'.
Cellular Location Nucleus.
Research Areas
Citations (0)

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Background

This gene encodes a transcription factor that is a memberof the leucine zipper family of DNA binding proteins. This proteinbinds as a homodimer to the cAMP-responsive element, an octamericpalindrome. The protein is phosphorylated by several proteinkinases, and induces transcription of genes in response to hormonalstimulation of the cAMP pathway. Alternate splicing of this generesults in two transcript variants encoding different isoforms.

References

Jablonski, K.A., et al. Diabetes 59(10):2672-2681(2010)Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Chen, G., et al. J. Neurosci. 30(39):13066-13077(2010)Serretti, A., et al. J Affect Disord (2010) In press :Melnikova, V.O., et al. PLoS ONE 5 (8), E12452 (2010) :

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$ 80.00
Cat# BP11705c
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