|Other Names||Gypsy retrotransposon integrase-like protein 1, GIN-1, Ty3/Gypsy integrase 1, Zinc finger H2C2 domain-containing protein, GIN1, TGIN1, ZH2C2|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Tissue Location||Widely expressed. Also found in tumors originating from parathyroid gland, colon, stomach, bladder, uterus and prostate.|
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The protein encoded by this gene belongs to the SMAD, afamily of proteins similar to the gene products of the Drosophilagene 'mothers against decapentaplegic' (Mad) and the C. elegansgene Sma. SMAD proteins are signal transducers and transcriptionalmodulators that mediate multiple signaling pathways. This proteinfunctions as a transcriptional modulator activated by transforminggrowth factor-beta and is thought to play a role in the regulationof carcinogenesis.
Ge, Q., et al. J. Cell. Physiol. 225(3):846-854(2010)Lee, J., et al. J. Biol. Chem. 285(34):26618-26627(2010)Roder, C., et al. Childs Nerv Syst (2010) In press :Valdes, A.M., et al. Arthritis Rheum. 62(8):2347-2352(2010)Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :
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