|Other Names||Zinc finger C2HC domain-containing protein 1B, ZC2HC1B, C6orf94, FAM164B|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
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This gene encodes a member of the RSK (ribosomal S6kinase) family of serine/threonine kinases. This kinase contains 2non-identical kinase catalytic domains and phosphorylates severalresidues of the S6 ribosomal protein. The kinase activity of thisprotein leads to an increase in protein synthesis and cellproliferation. Amplification of the region of DNA encoding thisgene and overexpression of this kinase are seen in some breastcancer cell lines. Alternate translational start sites have beendescribed and alternate transcriptional splice variants have beenobserved but have not been thoroughly characterized. [provided byRefSeq].
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Lai, K.P., et al. EMBO J. 29(17):2994-3006(2010)Treekitkarnmongkol, W., et al. World J. Gastroenterol. 16(32):4047-4054(2010)Fenton, T.R., et al. Biochem. Biophys. Res. Commun. 398(3):400-405(2010)Bian, C.X., et al. Biochem. Biophys. Res. Commun. 398(3):395-399(2010)
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