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LOC129293 Antibody (C-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q86V40
Other Accession NP_001074293.1
Clone Names 100408198
Peptide ID 100408198
Additional Information
Gene ID 129293
Other Names Metalloprotease TIKI1, 34--, TRAB domain-containing protein 2A, TRABD2A, C2orf89, TIKI1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms C2orf89, TIKI1
Function Metalloprotease that acts as a negative regulator of the Wnt signaling pathway by mediating the cleavage of the 8 N- terminal residues of a subset of Wnt proteins. Following cleavage, Wnt proteins become oxidized and form large disulfide-bond oligomers, leading to their inactivation. Able to cleave WNT3A, WNT5, but not WNT11. Required for head formation.
Cellular Location Cell membrane; Single-pass type I membrane protein
Research Areas
Citations (0)

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Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

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$ 80.00
Cat# BP11741b
(40 western blots)
Availability: In Stock
Bulk Size
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