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LOC129293 Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q86V40 |
|---|---|
| Other Accession | NP_001074293.1 |
| Clone Names | 100408198 |
| Gene ID | 129293 |
|---|---|
| Other Names | Metalloprotease TIKI1, 34--, TRAB domain-containing protein 2A, TRABD2A, C2orf89, TIKI1 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | TRABD2A |
|---|---|
| Synonyms | C2orf89, TIKI1 |
| Function | Metalloprotease that acts as a negative regulator of the Wnt signaling pathway by mediating the cleavage of the 8 N-terminal residues of a subset of Wnt proteins. Following cleavage, Wnt proteins become oxidized and form large disulfide-bond oligomers, leading to their inactivation. Able to cleave WNT3A, WNT5, but not WNT11. Required for head formation. |
| Cellular Location | Cell membrane; Single-pass type I membrane protein |
Research Areas
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
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$ 277.78
Cat# BP11741b
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