CCDC36 Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q8IYA8 |
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Clone Names | 100309056 |
Gene ID | 339834 |
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Other Names | Coiled-coil domain-containing protein 36, Cancer/testis antigen 74, CT74, CCDC36 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | IHO1 {ECO:0000303|PubMed:27723721, ECO:0000312|HGNC:HGNC:27945} |
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Function | Required for DNA double-strand breaks (DSBs) formation in unsynapsed regions during meiotic recombination. Probably acts by forming a complex with MEI4 and REC114, which activates DSBs formation in unsynapsed regions, an essential step to ensure completion of synapsis. Not required for HORMAD1 functions in pairing-independent synaptonemal complex formation, ATR recruitment to unsynapsed axes, meiotic silencing of unsynapsed chromatin (MSUC) or meiotic surveillance. |
Cellular Location | Chromosome {ECO:0000250|UniProtKB:Q6PDM4}. Note=Specifically localizes to unsynapsed chromosomal regions during meiosis. {ECO:0000250|UniProtKB:Q6PDM4} |
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Provided below are standard protocols that you may find useful for product applications.
Background
ZNF860 may be involved in transcriptional regulation (By similarity).
References
Muzny, D.M., et al. Nature 440(7088):1194-1198(2006)
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