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CCDC36 Antibody (C-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q8IYA8
Clone Names 100309056
Peptide ID 100309056
Additional Information
Gene ID 339834
Other Names Coiled-coil domain-containing protein 36, Cancer/testis antigen 74, CT74, CCDC36
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CCDC36 (HGNC:27945)
Function Required for DNA double-strand breaks (DSBs) formation in unsynapsed regions during meiotic recombination. Probably acts by forming a complex with MEI4 and REC114, which activates DSBs formation in unsynapsed regions, an essential step to ensure completion of synapsis. Not required for HORMAD1 functions in pairing-independent synaptonemal complex formation, ATR recruitment to unsynapsed axes, meiotic silencing of unsynapsed chromatin (MSUC) or meiotic surveillance.
Cellular Location Chromosome {ECO:0000250|UniProtKB:Q6PDM4}. Note=Specifically localizes to unsynapsed chromosomal regions during meiosis. {ECO:0000250|UniProtKB:Q6PDM4}
Research Areas
Citations (0)

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Background

ZNF860 may be involved in transcriptional regulation (By similarity).

References

Muzny, D.M., et al. Nature 440(7088):1194-1198(2006)

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$ 80.00
Cat# BP11750b
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