|Other Names||Coiled-coil domain-containing protein 110, Cancer/testis antigen 52, CT52, Cancer/testis antigen KM-HN-1, CCDC110, KMHN1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Tissue Location||Expressed specifically in testis. Also expressed in tumors of different origins|
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This gene encodes a pentaspan transmembrane glycoprotein.The protein localizes to membrane protrusions and is oftenexpressed on adult stem cells, where it is thought to function inmaintaining stem cell properties by suppressing differentiation.Mutations in this gene have been shown to result in retinitispigmentosa and Stargardt disease. Expression of this gene is alsoassociated with several types of cancer. This gene is expressedfrom at least five alternative promoters that are expressed in atissue-dependent manner. Multiple transcript variants encodingdifferent isoforms have been found for this gene. [provided byRefSeq].
Nakamura, M., et al. Hum. Pathol. 41(11):1516-1529(2010)Li, G., et al. Clin. Exp. Metastasis 27(7):517-527(2010)Mosing, M.A., et al. Twin Res Hum Genet 13(4):398-403(2010)Lugli, A., et al. Br. J. Cancer 103(3):382-390(2010)Cui, L., et al. PLoS ONE 5 (8), E12121 (2010) :
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