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CCDC110 Antibody (C-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q8TBZ0
Clone Names 91230030
Peptide ID 91230030
Additional Information
Other Names Coiled-coil domain-containing protein 110, Cancer/testis antigen 52, CT52, Cancer/testis antigen KM-HN-1, CCDC110, KMHN1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CCDC110
Synonyms KMHN1
Cellular Location Nucleus.
Tissue Location Expressed specifically in testis. Also expressed in tumors of different origins EMBL; AB080722; BAC81776.1; -; mRNA EMBL; BC028419; AAH28419.1; -; mRNA EMBL; BC038515; AAH38515.1; -; mRNA EMBL; AK097605; BAC05116.1; -; mRNA CCDS; CCDS3843.1; -. [Q8TBZ0-1] CCDS; CCDS47170.1; -. [Q8TBZ0-2] RefSeq; NP_001138883.1; NM_001145411.1. [Q8TBZ0-2] RefSeq; NP_689988.1; NM_152775.3. [Q8TBZ0-1] UniGene; Hs.41101; - ProteinModelPortal; Q8TBZ0; - SMR; Q8TBZ0; - BioGrid; 129157; 4 IntAct; Q8TBZ0; 2 STRING; 9606.ENSP00000306776; - iPTMnet; Q8TBZ0; - PhosphoSitePlus; Q8TBZ0; - BioMuta; CCDC110; - DMDM; 74730531; - PaxDb; Q8TBZ0; - PeptideAtlas; Q8TBZ0; - PRIDE; Q8TBZ0; - DNASU; 256309; - Ensembl; ENST00000307588; ENSP00000306776; ENSG00000168491. [Q8TBZ0-1] Ensembl; ENST00000393540; ENSP00000377172; ENSG00000168491. [Q8TBZ0-2] GeneID; 256309; - KEGG; hsa:256309; - UCSC; uc003ixu.5; human. [Q8TBZ0-1] CTD; 256309; - GeneCards; CCDC110; - HGNC; HGNC:28504; CCDC110 HPA; HPA038475; - MIM; 609488; gene neXtProt; NX_Q8TBZ0; - OpenTargets; ENSG00000168491; - PharmGKB; PA162381283; - eggNOG; ENOG410IFF1; Eukaryota eggNOG; ENOG410YGCT; LUCA GeneTree; ENSGT00710000106843; - HOGENOM; HOG000057285; - HOVERGEN; HBG081026; - InParanoid; Q8TBZ0; - PhylomeDB; Q8TBZ0; - TreeFam; TF335739; - BioCyc; ZFISH:ENSG00000168491-MONOMER; - GenomeRNAi; 256309; - PRO; PR:Q8TBZ0; - Proteomes; UP000005640; Chromosome 4 Bgee; ENSG00000168491; - CleanEx; HS_CCDC110; - ExpressionAtlas; Q8TBZ0; baseline and differential Genevisible; Q8TBZ0; HS GO; GO:0005737; C:cytoplasm; IDA:HPA GO; GO:0005794; C:Golgi apparatus; IDA:HPA GO; GO:0043231; C:intracellular membrane-bounded organelle; IDA:HPA GO; GO:0005730; C:nucleolus; IDA:HPA GO; GO:0005634; C:nucleus; IDA:HPA 1: Evidence at protein level; Alternative splicing; Coiled coil; Complete proteome; Nucleus; Phosphoprotein; Polymorphism; Reference proteome CHAIN 1 833 Coiled-coil domain-containing protein 110 /FTId=PRO_0000249076 COILED 431 778 MOD_RES 609 609 Phosphoserine {ECO:0000250|UniProtKB:Q3V125} VAR_SEQ 80 116 Missing (in isoform 2) /FTId=VSP_020365 VARIANT 209 209 P -> Q (in dbSNP:rs7699687) /FTId=VAR_050729 VARIANT 299 299 L -> M (in dbSNP:rs7698680) /FTId=VAR_050730 VARIANT 382 382 L -> M (in dbSNP:rs9999097) /FTId=VAR_050731 VARIANT 409 409 S -> F (in dbSNP:rs11132306) /FTId=VAR_050732 VARIANT 500 500 Y -> D (in dbSNP:rs59319722) /FTId=VAR_061577 VARIANT 614 614 I -> M (in dbSNP:rs35596415) /FTId=VAR_050733 VARIANT 669 669 Q -> R (in dbSNP:rs6827370) /FTId=VAR_050734 VARIANT 817 817 S -> L (in dbSNP:rs9683564) /FTId=VAR_050735 VARIANT 819 819 L -> M (in dbSNP:rs34800518) /FTId=VAR_050736 SEQUENCE 833 AA; 96726 MW; AE76D1328CBED1BA CRC64; MSPEKQHREE DEVDSVLLSA SKILNSSEGV KESGCSDTEY GCIAESENQI QPQSALKVLQ QQLESFQALR MQTLQNVSMV QSEISEILNK SIIEVENPQF SSEKNLVFGT RIEKDLPTEN QEENLSMEKS HHFEDSKTLH SVEEKLSGDS VNSLPQSVNV PSQIHSEDTL TLRTSTDNLS SNIIIHPSEN SDILKNYNNF YRFLPTAPPN VMSQADTVIL DKSKITVPFL KHGFCENLDD ICHSIKQMKE ELQKSHDGEV ALTNELQTLQ TDPDVHRNGK YDMSPIHQDK MNFIKEENLD GNLNEDIKSK RISELEALVK KLLPFRETVS KFHVHFCRKC KKLSKSEMHR GKKNEKNNKE IPITGKNITD LKFHSRVPRY TLSFLDQTKH EMKDKERQPF LVKQGSIISE NEKTSKVNSV TEQCVAKIQY LQNYLKESVQ IQKKVMELES ENLNLKSKMK PLIFTTQSLI QKVETYEKQL KNLVEEKSTI QSKLSKTEEY SKECLKEFKK IISKYNVLQG QNKTLEEKNI QLSLEKQQMM EALDQLKSKE HKTQSDMAIV NNENNRMSIE MEAMKTNILL IQDEKEMLEK KTHQLLKEKS SLGNELKESQ LEIIQLKEKE RLAKTEQETL LQIIETVKDE KLNLETTLQE STAARQIMER EIENIQTYQS TAEENFLQEI KNAKSEASIY KNSLSEIGKE CEMLSKMVME TKTDNQILKE ELKKHSQENI KFENSISRLT EDKILLENYV RSIENERDTL EFEMRHLQRE YLSLSDKICN QHNDPSKTTY ISRREKFHFD NYTHEDTSSP QSRPLASDLK GYFKVKDRTL KHH
Research Areas
Citations (0)

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Background

This gene encodes a pentaspan transmembrane glycoprotein.The protein localizes to membrane protrusions and is oftenexpressed on adult stem cells, where it is thought to function inmaintaining stem cell properties by suppressing differentiation.Mutations in this gene have been shown to result in retinitispigmentosa and Stargardt disease. Expression of this gene is alsoassociated with several types of cancer. This gene is expressedfrom at least five alternative promoters that are expressed in atissue-dependent manner. Multiple transcript variants encodingdifferent isoforms have been found for this gene. [provided byRefSeq].

References

Nakamura, M., et al. Hum. Pathol. 41(11):1516-1529(2010)Li, G., et al. Clin. Exp. Metastasis 27(7):517-527(2010)Mosing, M.A., et al. Twin Res Hum Genet 13(4):398-403(2010)Lugli, A., et al. Br. J. Cancer 103(3):382-390(2010)Cui, L., et al. PLoS ONE 5 (8), E12121 (2010) :

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$ 80.00
Cat# BP11757b
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