|Other Names||Rho-related GTP-binding protein RhoJ, Ras-like protein family member 7B, Tc10-like GTP-binding protein, RHOJ, ARHJ, RASL7B, RHOI, TCL|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Synonyms||ARHJ, RASL7B, RHOI, TCL|
|Function||GTP-binding protein with GTPase activity. Elicits the formation of F-actin-rich structures in fibroblasts and is involved in the regulation of cell morphology (By similarity).|
|Cellular Location||Cell membrane; Lipid-anchor; Cytoplasmic side|
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Provided below are standard protocols that you may find useful for product applications.
ARHJ belongs to the Rho family of small GTP-bindingproteins. Rho proteins regulate the dynamic assembly ofcytoskeletal components for several physiologic processes, such ascell proliferation and motility and the establishment of cellpolarity. They are also involved in pathophysiologic process, suchas cell transformation and metastasis.
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Lamesch, P., et al. Genomics 89(3):307-315(2007)Barrios-Rodiles, M., et al. Science 307(5715):1621-1625(2005)Nishikimi, A., et al. FEBS Lett. 579(5):1039-1046(2005)Ruusala, A., et al. FEBS Lett. 572 (1-3), 159-166 (2004) :
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