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SOX1 Antibody (N-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession O00570
Clone Names 71130123
Peptide ID 71130123
Additional Information
Other Names Transcription factor SOX-1, SOX1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SOX1
Function Transcriptional activator. May function as a switch in neuronal development. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity).
Cellular Location Nucleus.
Tissue Location Mainly expressed in the developing central nervous system EMBL; Y13436; CAA73847.1; -; Genomic_DNA EMBL; AL138691; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL; CH471085; EAX09158.1; -; Genomic_DNA CCDS; CCDS9523.1; - RefSeq; NP_005977.2; NM_005986.2 UniGene; Hs.202526; - ProteinModelPortal; O00570; - SMR; O00570; - BioGrid; 112539; 2 IntAct; O00570; 1 STRING; 9606.ENSP00000330218; - iPTMnet; O00570; - PhosphoSitePlus; O00570; - BioMuta; SOX1; - MaxQB; O00570; - PaxDb; O00570; - PeptideAtlas; O00570; - PRIDE; O00570; - ProteomicsDB; 47981; - Ensembl; ENST00000330949; ENSP00000330218; ENSG00000182968 GeneID; 6656; - KEGG; hsa:6656; - UCSC; uc001vsb.2; human CTD; 6656; - DisGeNET; 6656; - EuPathDB; HostDB:ENSG00000182968.4; - GeneCards; SOX1; - HGNC; HGNC:11189; SOX1 MIM; 602148; gene neXtProt; NX_O00570; - OpenTargets; ENSG00000182968; - PharmGKB; PA36026; - eggNOG; ENOG410IPZ0; Eukaryota eggNOG; ENOG41102MY; LUCA GeneTree; ENSGT00760000118988; - HOGENOM; HOG000231647; - HOVERGEN; HBG105663; - InParanoid; O00570; - KO; K09267; - OMA; HSRGPCP; - OrthoDB; EOG091G0F15; - PhylomeDB; O00570; - TreeFam; TF351735; - GenomeRNAi; 6656; - PRO; PR:O00570; - Proteomes; UP000005640; Chromosome 13 Bgee; ENSG00000182968; - CleanEx; HS_SOX1; - Genevisible; O00570; HS GO; GO:0005634; C:nucleus; NAS:UniProtKB GO; GO:0003677; F:DNA binding; NAS:UniProtKB GO; GO:0003700; F:DNA binding transcription factor activity; NAS:UniProtKB GO; GO:0000978; F:RNA polymerase II proximal promoter sequence-specific DNA binding; IDA:UniProtKB GO; GO:0000981; F:RNA polymerase II transcription factor activity, sequence-specific DNA binding; ISA:NTNU_SB GO; GO:0001077; F:transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding; IEA:Ensembl GO; GO:1990830; P:cellular response to leukemia inhibitory factor; IEA:Ensembl GO; GO:0006325; P:chromatin organization; NAS:UniProtKB GO; GO:0021884; P:forebrain neuron development; IEA:Ensembl GO; GO:0002089; P:lens morphogenesis in camera-type eye; IEA:Ensembl GO; GO:0001764; P:neuron migration; IEA:Ensembl GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB GO; GO:0021521; P:ventral spinal cord interneuron specification; IEA:Ensembl Gene3D; 1.10.30.10; -; 1 InterPro; IPR009071; HMG_box_dom InterPro; IPR036910; HMG_box_dom_sf InterPro; IPR031268; SOX-1 InterPro; IPR022097; SOX_fam PANTHER; PTHR10270:SF40; PTHR10270:SF40; 1 Pfam; PF00505; HMG_box; 1 Pfam; PF12336; SOXp; 1 SMART; SM00398; HMG; 1 SUPFAM; SSF47095; SSF47095; 1 PROSITE; PS50118; HMG_BOX_2; 1 1: Evidence at protein level; Activator; Complete proteome; DNA-binding; Nucleus; Reference proteome; Transcription; Transcription regulation CHAIN 1 391 Transcription factor SOX-1 /FTId=PRO_0000048712 DNA_BIND 51 119 HMG box. {ECO:0000255|PROSITE- ProRule:PRU00267} COMPBIAS 27 43 Poly-Gly COMPBIAS 145 150 Poly-Gly COMPBIAS 197 204 Poly-Ala COMPBIAS 280 288 Poly-Ala COMPBIAS 296 306 Poly-Ala COMPBIAS 357 364 Poly-Ala CONFLICT 165 165 A -> P (in Ref. 1; CAA73847) CONFLICT 180 180 G -> A (in Ref. 1; CAA73847) CONFLICT 226 227 AH -> RT (in Ref. 1; CAA73847) CONFLICT 287 290 Missing (in Ref. 1; CAA73847) SEQUENCE 391 AA; 39023 MW; DD519BA97CF5E052 CRC64; MYSMMMETDL HSPGGAQAPT NLSGPAGAGG GGGGGGGGGG GGGAKANQDR VKRPMNAFMV WSRGQRRKMA QENPKMHNSE ISKRLGAEWK VMSEAEKRPF IDEAKRLRAL HMKEHPDYKY RPRRKTKTLL KKDKYSLAGG LLAAGAGGGG AAVAMGVGVG VGAAAVGQRL ESPGGAAGGG YAHVNGWANG AYPGSVAAAA AAAAMMQEAQ LAYGQHPGAG GAHPHAHPAH PHPHHPHAHP HNPQPMHRYD MGALQYSPIS NSQGYMSASP SGYGGLPYGA AAAAAAAAGG AHQNSAVAAA AAAAAASSGA LGALGSLVKS EPSGSPPAPA HSRAPCPGDL REMISMYLPA GEGGDPAAAA AAAAQSRLHS LPQHYQGAGA GVNGTVPLTH I
Research Areas
Citations (0)

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Background

C18orf8 is an uncharacterized protein.

References

Olsen, J.V., et al. Cell 127(3):635-648(2006)Olsen, J.V., et al. Cell 127(3):635-648(2006)

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$ 80.00
Cat# BP11764a
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