|Other Names||Uncharacterized protein C18orf8, Colon cancer-associated protein Mic1, Mic-1, C18orf8, MIC1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
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This gene encodes a member of the Rho GTPase family, whosemembers play a key role in the regulation of actin cytoskeletonorganization in response to extracellular growth factors. Thisparticular family member has been implicated in the regulation ofneuronal morphology and endosomal trafficking. The gene localizesto chromosome 17 and is the centromeric neighbor of thebreast-ovarian cancer susceptibility gene BRCA1. [provided byRefSeq].
Tanaka, H., et al. J. Biol. Chem. 281(15):10355-10364(2006)Kim, Y.S., et al. Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. 142(4):410-415(2005)Kakimoto, T., et al. J. Biol. Chem. 279(14):14104-14110(2004)Naud, N., et al. Biochem. J. 372 (PT 1), 105-112 (2003) :Fujita, H., et al. J. Biol. Chem. 277(47):45428-45434(2002)
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