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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   RHEB Antibody (C-term) Blocking peptide   

RHEB Antibody (C-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q15382
Clone Names 71211161
Peptide ID 71211161
Additional Information
Gene ID 6009
Other Names GTP-binding protein Rheb, Ras homolog enriched in brain, RHEB, RHEB2
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms RHEB2
Function Activates the protein kinase activity of mTORC1, and thereby plays a role in the regulation of apoptosis. Stimulates the phosphorylation of S6K1 and EIF4EBP1 through activation of mTORC1 signaling. Has low intrinsic GTPase activity.
Cellular Location Endomembrane system {ECO:0000269|PubMed:22002721, ECO:0000305}; Lipid-anchor {ECO:0000269|PubMed:22002721, ECO:0000305}; Cytoplasmic side {ECO:0000269|PubMed:15489334, ECO:0000305}. Golgi apparatus membrane; Lipid-anchor; Cytoplasmic side. Cytoplasm, cytosol. Endoplasmic reticulum membrane; Lipid-anchor; Cytoplasmic side
Tissue Location Ubiquitous. Highest levels observed in skeletal and cardiac muscle.
Research Areas
Citations (0)

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Receptor-activated non-selective cation channel involved in detection of sensations such as coolness, by being activated by cold temperature below 25 degrees Celsius. Activated by icilin, eucalyptol, menthol, cold and modulation of intracellular pH. Involved in menthol sensation. Permeable for monovalent cations sodium, potassium, and cesium and divalent cation calcium. Temperature sensing is tightly linked to voltage-dependent gating. Activated upon depolarization, changes in temperature resulting in graded shifts of its voltage-dependent activation curves. The chemical agonists menthol functions as a gating modifier, shifting activation curves towards physiological membrane potentials. Temperature sensitivity arises from a tenfold difference in the activation energies associated with voltage-dependent opening and closing.


Yee, N.S., et al. Cancer Lett. 297(1):49-55(2010)Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Kuhn, F.J., et al. J. Biol. Chem. 285(35):26806-26814(2010)Gkika, D., et al. Oncogene 29(32):4611-4616(2010)Van Haute, C., et al. ScientificWorldJournal 10, 1597-1611 (2010) :

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$ 80.00
Cat# BP11767b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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