PLEKHA4 Antibody (N-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9H4M7 |
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Clone Names | 80917057 |
Gene ID | 57664 |
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Other Names | Pleckstrin homology domain-containing family A member 4, PH domain-containing family A member 4, Phosphoinositol 3-phosphate-binding protein 1, PEPP-1, PLEKHA4, PEPP1 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | PLEKHA4 |
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Synonyms | PEPP1 |
Function | Binds specifically to phosphatidylinositol 3-phosphate (PtdIns3P), but not to other phosphoinositides. |
Cellular Location | Cytoplasm. Membrane; Peripheral membrane protein |
Tissue Location | Highly expressed in melanoma. Detected at low levels in heart, skeletal muscle, kidney, liver and small intestine |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the synuclein family ofproteins which are believed to be involved in the pathogenesis ofneurodegenerative diseases. Mutations in this gene have also beenassociated with breast tumor development.
References
Li, M., et al. J. Biol. Chem. 285(40):30480-30488(2010)Nishioka, K., et al. Arch. Neurol. 67(8):970-975(2010)Ye, Q., et al. Oncol. Rep. 23(2):429-436(2010)Ye, Q., et al. World J. Gastroenterol. 15(40):5035-5043(2009)Hu, H., et al. Clin. Cancer Res. 15(17):5485-5493(2009)
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