|Other Names||Mucin-3B, MUC-3B, Intestinal mucin-3B, MUC3B|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Major glycoprotein component of a variety of mucus gels. Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces (By similarity).|
|Cellular Location||Membrane; Single-pass membrane protein|
|Tissue Location||Fetal and adult small intestine and fetal and adult colon.|
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The protein encoded by this gene is a member of the S100family of proteins containing 2 EF-hand calcium-binding motifs.S100 proteins are localized in the cytoplasm and/or nucleus of awide range of cells, and involved in the regulation of a number ofcellular processes such as cell cycle progression anddifferentiation. S100 genes include at least 13 members which arelocated as a cluster on chromosome 1q21. This protein may functionin stimulation of Ca2+-induced Ca2+ release, inhibition ofmicrotubule assembly, and inhibition of protein kinase C-mediatedphosphorylation. Reduced expression of this protein has beenimplicated in cardiomyopathies.
Marlatt, N.M., et al. Protein Expr. Purif. 73(1):58-64(2010)van Dieck, J., et al. FEBS Lett. 584(15):3269-3274(2010)Sviatoha, V., et al. Melanoma Res. 20(2):118-125(2010)DeRycke, M.S., et al. Am. J. Clin. Pathol. 132(6):846-856(2009)Yusenko, M.V., et al. Int. J. Biol. Sci. 5(6):517-527(2009)
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