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p21WAF1 Antibody (Center H450) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession O60294
Clone Names 80722078
Additional Information
Gene ID 9836
Other Names tRNA wybutosine-synthesizing protein 4, tRNA yW-synthesizing protein 4, Leucine carboxyl methyltransferase 2, tRNA(Phe) (7-(3-amino-3-(methoxycarbonyl)propyl)wyosine(37)-N)-methoxycarbonyltransferase, tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-O)-methyltransferase, LCMT2, KIAA0547, TYW4
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name LCMT2
Synonyms KIAA0547, TYW4
Function Probable S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA (By similarity). May methylate the carboxyl group of leucine residues to form alpha-leucine ester residues.
Research Areas
Citations (0)
citation

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Background

This gene is a member of the Nod1/Apaf-1 family andencodes a protein with two caspase recruitment (CARD) domains andsix leucine-rich repeats (LRRs). The protein is primarily expressedin the peripheral blood leukocytes. It plays a role in the immuneresponse to intracellular bacterial lipopolysaccharides (LPS) byrecognizing the muramyl dipeptide (MDP) derived from them andactivating the NFKB protein. Mutations in this gene have beenassociated with Crohn disease and Blau syndrome. [provided byRefSeq].

References

Sehgal, R., et al. Dis. Colon Rectum 53(11):1487-1494(2010)Cadwell, K. Gastroenterology 139(5):1448-1450(2010)Lacher, M., et al. J. Pediatr. Surg. 45(8):1591-1597(2010)Kramer, M., et al. BMC Res Notes 3, 224 (2010) :Kanazawa, N., et al. Blood 105(3):1195-1197(2005)

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$ 277.78
Cat# BP11778c
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