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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   NIX Antibody (Center) Blocking peptide   

NIX Antibody (Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession O60238
Clone Names 80924001
Peptide ID 80924001
Additional Information
Gene ID 665
Other Names BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like, Adenovirus E1B19K-binding protein B5, BCL2/adenovirus E1B 19 kDa protein-interacting protein 3A, NIP3-like protein X, NIP3L, BNIP3L, BNIP3A, BNIP3H, NIX
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms BNIP3A, BNIP3H, NIX
Function Induces apoptosis. Interacts with viral and cellular anti-apoptosis proteins. Can overcome the suppressors BCL-2 and BCL-XL, although high levels of BCL-XL expression will inhibit apoptosis. Inhibits apoptosis induced by BNIP3. Involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage, participates to mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria. The physical interaction of SPATA18/MIEAP, BNIP3 and BNIP3L/NIX at the mitochondrial outer membrane regulates the opening of a pore in the mitochondrial double membrane in order to mediate the translocation of lysosomal proteins from the cytoplasm to the mitochondrial matrix. May function as a tumor suppressor.
Cellular Location Nucleus envelope. Endoplasmic reticulum. Mitochondrion outer membrane. Membrane; Single-pass membrane protein. Note=Colocalizes with SPATA18 at the mitochondrion outer membrane
Research Areas
Citations (0)

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NUP160 is 1 of up to 60 proteins that make up the 120-MDnuclear pore complex, which mediates nucleoplasmictransport.


Mishra, R.K., et al. Nat. Cell Biol. 12(2):164-169(2010)Platani, M., et al. Mol. Biol. Cell 20(24):5260-5275(2009)Leksa, N.C., et al. Structure 17(8):1082-1091(2009)Zuccolo, M., et al. EMBO J. 26(7):1853-1864(2007)Glavy, J.S., et al. Proc. Natl. Acad. Sci. U.S.A. 104(10):3811-3816(2007)

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$ 80.00
Cat# BP11786c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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