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CBLN2 Antibody (C-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q8IUK8
Other Accession NP_872317.1
Clone Names 91201164
Additional Information
Gene ID 147381
Other Names Cerebellin-2, CBLN2
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CBLN2
Function Acts as a synaptic organizer in specific subsets of neurons in the brain (By similarity). Essential for long-term maintenance but not establishment of excitatory synapses (By similarity).
Cellular Location Secreted {ECO:0000250|UniProtKB:Q8BGU2}.
Research Areas
Citations (0)
citation

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Background

WTIP may monitor slit diaphragm protein assembly, a specialized adherens junction characteristic of podocytes. In case of podocyte injury, it shuttles into the nucleus and acts as a transcription regulator that represses WT1-dependent transcription regulation, thereby translating changes in slit diaphragm structure into altered gene expression and a less differentiated phenotype (By similarity).

References

Grant, S.F., et al. J. Pediatr. 155(6):909-913(2009)Baranzini, S.E., et al. Hum. Mol. Genet. 18(4):767-778(2009)Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)Kavety, B., et al. Brain Res. Mol. Brain Res. 27(1):152-156(1994)

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$ 277.78
Cat# BP11835b
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