CBLN2 Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q8IUK8 |
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Other Accession | NP_872317.1 |
Clone Names | 91201164 |
Gene ID | 147381 |
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Other Names | Cerebellin-2, CBLN2 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | CBLN2 |
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Function | Acts as a synaptic organizer in specific subsets of neurons in the brain (By similarity). Essential for long-term maintenance but not establishment of excitatory synapses (By similarity). |
Cellular Location | Secreted {ECO:0000250|UniProtKB:Q8BGU2}. |
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Provided below are standard protocols that you may find useful for product applications.
Background
WTIP may monitor slit diaphragm protein assembly, a specialized adherens junction characteristic of podocytes. In case of podocyte injury, it shuttles into the nucleus and acts as a transcription regulator that represses WT1-dependent transcription regulation, thereby translating changes in slit diaphragm structure into altered gene expression and a less differentiated phenotype (By similarity).
References
Grant, S.F., et al. J. Pediatr. 155(6):909-913(2009)Baranzini, S.E., et al. Hum. Mol. Genet. 18(4):767-778(2009)Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)Kavety, B., et al. Brain Res. Mol. Brain Res. 27(1):152-156(1994)
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