PDE1B Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q01064 |
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Clone Names | 101008227 |
Gene ID | 5153 |
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Other Names | Calcium/calmodulin-dependent 3', 5'-cyclic nucleotide phosphodiesterase 1B, Cam-PDE 1B, 63 kDa Cam-PDE, PDE1B, PDE1B1, PDES1B |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | PDE1B (HGNC:8775) |
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Synonyms | PDES1B |
Function | Cyclic nucleotide phosphodiesterase with a dual specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes (PubMed:8855339, PubMed:9419816, PubMed:15260978). Has a preference for cGMP as a substrate (PubMed:9419816). |
Cellular Location | Cytoplasm, cytosol. |
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this intronless gene belongs to theGSK-3-binding protein family. Studies show that this protein playsa role as a positive regulator of the WNT signaling pathway. It maybe upregulated in tumor progression.
References
Lee, D.Y., et al. Menopause 17(5):1064-1070(2010)Liu, G.P., et al. Neurobiol. Aging 29(9):1348-1358(2008)Stoothoff, W.H., et al. J. Biol. Chem. 280(1):270-276(2005)Deloukas, P., et al. Nature 429(6990):375-381(2004)Freemantle, S.J., et al. Gene 291 (1-2), 17-27 (2002) :
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