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SOCS4 Antibody (Center) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q8WXH5 |
|---|---|
| Clone Names | 101008229 |
| Gene ID | 122809 |
|---|---|
| Other Names | Suppressor of cytokine signaling 4, SOCS-4, Suppressor of cytokine signaling 7, SOCS-7, SOCS4, SOCS7 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | SOCS4 |
|---|---|
| Synonyms | SOCS7 |
| Function | SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. Substrate- recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Inhibits EGF signaling by mediating the degradation of the Tyr-phosphorylated EGF receptor/EGFR. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Phosphorylation of cardiac myosin heavy chains (see MYH7B,MIM 609928) and light chains (see MYL2, MIM 160781) by a kinase,such as MYLK3, potentiates the force and rate of cross-bridgerecruitment in cardiac myocytes (Chan et al., 2008 [PubMed18202317]).
References
Al-Sadi, R., et al. J. Immunol. 180(8):5653-5661(2008)Chan, J.Y., et al. Circ. Res. 102(5):571-580(2008)Seguchi, O., et al. J. Clin. Invest. 117(10):2812-2824(2007)
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