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PYCR2 Antibody (Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q96C36
Clone Names 101008281
Peptide ID 101008281
Additional Information
Gene ID 29920
Other Names Pyrroline-5-carboxylate reductase 2, P5C reductase 2, P5CR 2, PYCR2
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name PYCR2
Function Housekeeping enzyme that catalyzes the last step in proline biosynthesis. In some cell types, such as erythrocytes, its primary function may be the generation of NADP(+). Can utilize both NAD and NADP. Has higher affinity for NADP, but higher catalytic efficiency with NADH.
Cellular Location Cytoplasm.
Tissue Location Detected in erythrocytes (at protein level).
Research Areas
Citations (0)

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This gene encodes a member of the Ser/Thr protein kinasefamily and the TGFB receptor subfamily. The encoded protein is atransmembrane protein that has a protein kinase domain, forms aheterodimeric complex with another receptor protein, and bindsTGF-beta. This receptor/ligand complex phosphorylates proteins,which then enter the nucleus and regulate the transcription of asubset of genes related to cell proliferation. Mutations in thisgene have been associated with Marfan Syndrome, Loeys-Deitz AorticAneurysm Syndrome, and the development of various types of tumors.Alternatively spliced transcript variants encoding differentisoforms have been characterized.


Inamoto, S., et al. Cardiovasc. Res. 88(3):520-529(2010)Bianchini, G., et al. J. Clin. Oncol. 28(28):4316-4323(2010)Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Kim, J.N., et al. Toxicology 275 (1-3), 29-35 (2010) :Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :

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$ 80.00
Cat# BP11852c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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