|Other Names||Growth arrest-specific protein 1, GAS-1, GAS1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Specific growth arrest protein involved in growth suppression. Blocks entry to S phase. Prevents cycling of normal and transformed cells.|
|Cellular Location||Cell membrane; Lipid-anchor, GPI-anchor|
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Provided below are standard protocols that you may find useful for product applications.
Growth arrest-specific 1 plays a role in growthsuppression. GAS1 blocks entry to S phase and prevents cycling ofnormal and transformed cells. Gas1 is a putative tumor suppressorgene.
Ribeiro, L.A., et al. Am. J. Med. Genet. A 152A (7), 1688-1694 (2010) :Johnatty, S.E., et al. PLoS Genet. 6 (7), E1001016 (2010) :Rittie, L., et al. Aging Cell 8(6):738-751(2009)Zhao, L., et al. J. Biol. Chem. 284(39):26273-26285(2009)Dominguez-Monzon, G., et al. Int. J. Dev. Neurosci. 27(4):305-313(2009)
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