|Other Names||Protein shisa-9, SHISA9|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Regulator of short-term neuronal synaptic plasticity in the dentate gyrus. Associates with AMPA receptors (ionotropic glutamate receptors) in synaptic spines and promotes AMPA receptor desensitization at excitatory synapses (By similarity).|
|Cellular Location||Cell projection, dendritic spine membrane; Single-pass type I membrane protein Cell junction, synapse|
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Provided below are standard protocols that you may find useful for product applications.
SHISA9 is a regulator of short-term neuronal synaptic plasticity in the dentate gyrus. Associates with AMPA receptors (ionotropic glutamate receptors) in synaptic spines and promotes AMPA receptor desensitization at excitatory synapses (By similarity).
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :von Engelhardt, J., et al. Science 327(5972):1518-1522(2010)Adkins, D.E., et al. Mol. Psychiatry (2010) In press :O'Donovan, M.C., et al. Nat. Genet. 40(9):1053-1055(2008)
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