KCNH6 Antibody (Center) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9H252 |
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Clone Names | 101008155 |
Gene ID | 81033 |
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Other Names | Potassium voltage-gated channel subfamily H member 6, Ether-a-go-go-related gene potassium channel 2, ERG-2, Eag-related protein 2, Ether-a-go-go-related protein 2, hERG-2, hERG2, Voltage-gated potassium channel subunit Kv112, KCNH6, ERG2 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | KCNH6 |
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Synonyms | ERG2 |
Function | Pore-forming (alpha) subunit of voltage-gated potassium channel. Elicits a slowly activating, rectifying current (By similarity). Channel properties may be modulated by cAMP and subunit assembly. |
Cellular Location | Membrane; Multi-pass membrane protein. |
Tissue Location | Expressed in prolactin-secreting adenomas. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Voltage-gated potassium (Kv) channels represent the mostcomplex class of voltage-gated ion channels from both functionaland structural standpoints. Their diverse functions includeregulating neurotransmitter release, heart rate, insulin secretion,neuronal excitability, epithelial electrolyte transport, smoothmuscle contraction, and cell volume. This gene encodes a member ofthe potassium channel, voltage-gated, subfamily H. This member is apore-forming (alpha) subunit. Several alternatively splicedtranscript variants have been identified from this gene, but thefull-length nature of only two transcript variants has beendetermined.
References
Liu, B.C., et al. Prog. Neuropsychopharmacol. Biol. Psychiatry 34(3):506-509(2010)Gutman, G.A., et al. Pharmacol. Rev. 57(4):473-508(2005)Bauer, C.K., et al. Pflugers Arch. 445(5):589-600(2003)Ganetzky, B., et al. Ann. N. Y. Acad. Sci. 868, 356-369 (1999) :
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