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C1QC Antibody (Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession P02747
Clone Names 101008195
Peptide ID 101008195
Additional Information
Gene ID 714
Other Names Complement C1q subcomponent subunit C, C1QC, C1QG
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name C1QC
Synonyms C1QG
Function C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.
Cellular Location Secreted.
Research Areas
Citations (0)

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This gene encodes a major constituent of the humancomplement subcomponent C1q. C1q associates with C1r and C1s inorder to yield the first component of the serum complement system.A deficiency in C1q has been associated with lupus erythematosusand glomerulonephritis. C1q is composed of 18 polypeptide chains:six A-chains, six B-chains, and six C-chains. Each chain contains acollagen-like region located near the N-terminus, and a C-terminalglobular region. The A-, B-, and C-chains are arranged in the orderA-C-B on chromosome 1. This gene encodes the C-chain polypeptide ofhuman complement subcomponent C1q. Alternatively spliced transcriptvariants that encode the same protein have been found for thisgene.


Fraser, D.A., et al. J. Immunol. 185(7):3932-3939(2010)Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Rafiq, S., et al. Clin. Exp. Immunol. 161(2):284-289(2010)Han, S., et al. Hum. Immunol. 71(7):727-730(2010)Rajaraman, P., et al. Cancer Epidemiol. Biomarkers Prev. 19(5):1356-1361(2010)

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$ 80.00
Cat# BP11931c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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