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TMEM206 Blocking Peptide (C-term)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9H813 |
|---|---|
| Other Accession | NP_060722.2 |
| Gene ID | 55248 |
|---|---|
| Other Names | Transmembrane protein 206, TMEM206, C1orf75 |
| Target/Specificity | The synthetic peptide sequence is selected from aa 335-348 of HUMAN TMEM206 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | PACC1 (HGNC:25593) |
|---|---|
| Function | Chloride channel gated by pH that facilitates the entry of chloride ions into cells upon exposure to extracellular acidic pH (PubMed:31023925, PubMed:31318332). Involved in acidosis-induced cell death by mediating chloride influx and subsequent cell swelling (PubMed:31023925, PubMed:31318332). |
| Cellular Location | Cell membrane; Multi-pass membrane protein |
| Tissue Location | Widely expressed, with highest expression in brain. |
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Provided below are standard protocols that you may find useful for product applications.
Background
TMEM206 belongs to the TMEM206 family.
References
Lamesch, P., et al. Genomics 89(3):307-315(2007)
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