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LGALS3 Antibody (C-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession P17931
Clone Names 101008052
Peptide ID 101008052
Additional Information
Gene ID 3958
Other Names Galectin-3, Gal-3, 35 kDa lectin, Carbohydrate-binding protein 35, CBP 35, Galactose-specific lectin 3, Galactoside-binding protein, GALBP, IgE-binding protein, L-31, Laminin-binding protein, Lectin L-29, Mac-2 antigen, LGALS3, MAC2
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms MAC2
Function Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity). In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.
Cellular Location Cytoplasm. Nucleus. Secreted. Note=Secreted by a non-classical secretory pathway and associates with the cell surface
Tissue Location A major expression is found in the colonic epithelium. It is also abundant in the activated macrophages Expressed in fetal membranes.
Research Areas
Citations (0)

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This gene encodes a member of the galectin family ofcarbohydrate binding proteins. Members of this protein family havean affinity for beta-galactosides. The encoded protein ischaracterized by an N-terminal proline-rich tandem repeat domainand a single C-terminal carbohydrate recognition domain. Thisprotein can self-associate through the N-terminal domain allowingit to bind to multivalent saccharide ligands. This proteinlocalizes to the extracellular matrix, the cytoplasm and thenucleus. This protein plays a role in numerous cellular functionsincluding apoptosis, innate immunity, cell adhesion and T-cellregulation. Alternate splicing results in multiple transcriptvariants.


Salomonsson, E., et al. J. Biol. Chem. 285(45):35079-35091(2010)Debierre-Grockiego, F., et al. J. Biol. Chem. 285(43):32744-32750(2010)Zhou, J.Y., et al. J. Proteome Res. 9(10):5133-5141(2010)Markowska, A.I., et al. J. Exp. Med. 207(9):1981-1993(2010)Mazurek, N., et al. J. Biol. Chem. 275(46):36311-36315(2000)

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$ 80.00
Cat# BP11938b
(40 western blots)
Availability: In Stock
Bulk Size
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