SLC16A6 Antibody (Center) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | O15403 |
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Clone Names | 101008073 |
Gene ID | 9120 |
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Other Names | Monocarboxylate transporter 7, MCT 7, Monocarboxylate transporter 6, MCT 6, Solute carrier family 16 member 6, SLC16A6, MCT6, MCT7 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | SLC16A6 {ECO:0000250|UniProtKB:Q7TMR7, ECO:0000312|HGNC:HGNC:10927} |
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Function | Monocarboxylate transporter selective for taurine. May associate with BSG/CD147 or EMB/GP70 ancillary proteins to mediate facilitative efflux or influx of taurine across the plasma membrane. The transport is pH- and sodium-independent. Rather low-affinity, is likely effective for taurine transport in tissues where taurine is present at high concentrations. |
Cellular Location | Basolateral cell membrane {ECO:0000250|UniProtKB:Q7TMR7}; Multi-pass membrane protein |
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Provided below are standard protocols that you may find useful for product applications.
Background
SLC16A6 is a proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate (By similarity).
References
Olsen, J.V., et al. Cell 127(3):635-648(2006)Olsen, J.V., et al. Cell 127(3):635-648(2006)Murakami, Y., et al. Drug Metab. Dispos. 33(12):1845-1851(2005)Halestrap, A.P., et al. Pflugers Arch. 447(5):619-628(2004)Halestrap, A.P., et al. Biochem. J. 343 PT 2, 281-299 (1999) :
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