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ZNF384 Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q8TF68 |
|---|---|
| Clone Names | 101008082 |
| Gene ID | 171017 |
|---|---|
| Other Names | Zinc finger protein 384, CAG repeat protein 1, CAS-interacting zinc finger protein, Nuclear matrix transcription factor 4, Nuclear matrix protein 4, Trinucleotide repeat-containing gene 1 protein, ZNF384, CAGH1, CIZ, NMP4, TNRC1 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | ZNF384 |
|---|---|
| Synonyms | CAGH1, CIZ, NMP4, TNRC1 |
| Function | Transcription factor that binds the consensus DNA sequence [GC]AAAAA. Seems to bind and regulate the promoters of MMP1, MMP3, MMP7 and COL1A1 (By similarity). |
| Cellular Location | Nucleus. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene contains long CAG trinucleotide repeats codingconsecutive glutamine residues. The gene product may functions as atranscription factor, with a potential role in the regulation ofneurodevelopment or neuroplasticity. The protein appears to bindand regulate the promoters of MMP1, MMP3, MMP7 and COL1A1. Studiesin mouse suggest that nuclear matrix transcription factors(NP/NMP4) may be part of a general mechanical pathway that couplescell construction and function during extracellular matrixremodeling. Multiple transcript variants encoding several isoformshave been found for this gene.
References
Alves, J., et al. Biochem. Biophys. Res. Commun. 384(4):495-500(2009)Zhong, C.H., et al. Leukemia 22(4):723-729(2008)Janssen, H., et al. Exp. Cell Res. 312(7):1194-1204(2006)La Starza, R., et al. Leukemia 19(9):1696-1699(2005)Martini, A., et al. Cancer Res. 62(19):5408-5412(2002)
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