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SAT2 Antibody (Center) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q96F10 |
|---|---|
| Clone Names | 101008190 |
| Gene ID | 112483 |
|---|---|
| Other Names | Diamine acetyltransferase 2, Polyamine N-acetyltransferase 2, Spermidine/spermine N(1)-acetyltransferase 2, Thialysine N-epsilon-acetyltransferase, SAT2, SSAT2 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | SAT2 (HGNC:23160) |
|---|---|
| Function | Catalyzes the N-acetylation of the amino acid thialysine (S- (2-aminoethyl)-L-cysteine), a L-lysine analog with the 4-methylene group substituted with a sulfur (PubMed:15283699). May also catalyze acetylation of polyamines, such as norspermidine, spermidine or spermine (PubMed:12803540). However, ability to acetylate polyamines is weak, suggesting that it does not act as a diamine acetyltransferase in vivo (PubMed:15283699). |
| Cellular Location | Cytoplasm. Note=Intracellular organelles. |
| Tissue Location | Widely expressed (PubMed:15283699, PubMed:12803540). Under physiological conditions, SSAT2 is expressed at lower level that SSAT1 (SSAT). Many tissues express only SSAT1, several tissues express both SSAT1 and SSAT2, and bone, cervix, ovary and pineal gland expressed only SSAT2 (PubMed:12803540) |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
SAT2 is an enzyme which catalyzes the acetylation of polyamines. Substrate specificity: norspermidine > spermidine = spermine >> N(1)acetylspermine = putrescine.
References
Guey, L.T., et al. Eur. Urol. 57(2):283-292(2010)Hosgood, H.D. III, et al. Respir Med 103(12):1866-1870(2009)Shen, M., et al. Environ. Mol. Mutagen. 50(4):285-290(2009)Sun, H., et al. Oncol. Rep. 20(5):1229-1235(2008)Hosgood, H.D. III, et al. Carcinogenesis 29(10):1938-1943(2008)
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