|Other Names||TELO2-interacting protein 2, TTI2, C8orf41|
|Target/Specificity||The synthetic peptide sequence is selected from aa 56-69 of HUMAN TTI2|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs.|
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Provided below are standard protocols that you may find useful for product applications.
The function of this protein remains unknown.
Hurov, K.E., et al. Genes Dev. 24(17):1939-1950(2010)
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