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C8orf41 Blocking Peptide (N-term)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q6NXR4 |
|---|---|
| Other Accession | NP_079391.2 |
| Gene ID | 80185 |
|---|---|
| Other Names | TELO2-interacting protein 2, TTI2, C8orf41 |
| Target/Specificity | The synthetic peptide sequence is selected from aa 56-69 of HUMAN TTI2 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | TTI2 |
|---|---|
| Synonyms | C8orf41 |
| Function | Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. |
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Provided below are standard protocols that you may find useful for product applications.
Background
The function of this protein remains unknown.
References
Hurov, K.E., et al. Genes Dev. 24(17):1939-1950(2010)
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