|Other Names||2-acylglycerol O-acyltransferase 3, Acyl-CoA:monoacylglycerol acyltransferase 3, MGAT3, Diacylglycerol O-acyltransferase candidate 7, hDC7, Diacylglycerol acyltransferase 2-like protein 7, Monoacylglycerol O-acyltransferase 3, MOGAT3, DC7, DGAT2L7|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the formation of diacylglycerol from 2- monoacylglycerol and fatty acyl-CoA. Also able to catalyze the terminal step in triacylglycerol synthesis by using diacylglycerol and fatty acyl-CoA as substrates. Has a preference toward palmitoyl-CoA and oleoyl-CoA. May be involved in absorption of dietary fat in the small intestine by catalyzing the resynthesis of triacylglycerol in enterocytes.|
|Cellular Location||Endoplasmic reticulum membrane; Multi-pass membrane protein|
|Tissue Location||Selectively expressed in the digestive system. Highly expressed in the ileum, and at lower level in jejunum, duodenum, colon, cecum and the rectum. Not expressed in the stomach and the esophagus and trachea. Expressed at very low level in liver.|
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Provided below are standard protocols that you may find useful for product applications.
Acyl-CoA:monoacylglycerol acyltransferase (MOGAT; EC220.127.116.11) catalyzes the synthesis of diacylglycerol from2-monoacylglycerol and fatty acyl-CoA (Cheng et al., 2003 [PubMed12618427]).
Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)Cheng, D., et al. J. Biol. Chem. 278(16):13611-13614(2003)Winter, A., et al. Cytogenet. Genome Res. 102 (1-4), 42-47 (2003) :
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