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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   MED7 Antibody (Center) Blocking peptide   

MED7 Antibody (Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession O43513
Clone Names 81028089
Peptide ID 81028089
Additional Information
Gene ID 9443
Other Names Mediator of RNA polymerase II transcription subunit 7, hMED7, Activator-recruited cofactor 34 kDa component, ARC34, Cofactor required for Sp1 transcriptional activation subunit 9, CRSP complex subunit 9, Mediator complex subunit 7, RNA polymerase transcriptional regulation mediator subunit 7 homolog, Transcriptional coactivator CRSP33, MED7, ARC34, CRSP9
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name MED7
Synonyms ARC34, CRSP9
Function Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Cellular Location Nucleus.
Research Areas
Citations (0)

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The activation of gene transcription is a multistepprocess that is triggered by factors that recognize transcriptionalenhancer sites in DNA. These factors work with co-activators todirect transcriptional initiation by the RNA polymerase IIapparatus. The protein encoded by this gene is a subunit of theCRSP (cofactor required for SP1 activation) complex, which, alongwith TFIID, is required for efficient activation by SP1. Thisprotein is also a component of other multisubunit complexes e.g.thyroid hormone receptor-(TR-) associated proteins which interactwith TR and facilitate TR function on DNA templates in conjunctionwith initiation factors and cofactors. Two transcript variantsencoding the same protein have been found for this gene. [providedby RefSeq].


Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :Sato, S., et al. Mol. Cell 14(5):685-691(2004)Tomomori-Sato, C., et al. J. Biol. Chem. 279(7):5846-5851(2004)Sato, S., et al. J. Biol. Chem. 278(17):15123-15127(2003)Ryu, S., et al. Proc. Natl. Acad. Sci. U.S.A. 96(13):7137-7142(1999)

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$ 80.00
Cat# BP11961c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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