|Other Names||Endothelin-1, Preproendothelin-1, PPET1, Endothelin-1, ET-1, Big endothelin-1, EDN1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Endothelins are endothelium-derived vasoconstrictor peptides.|
|Tissue Location||Expressed in lung, placental stem villi vessels and in cultured placental vascular smooth muscle cells|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is proteolyticallyprocessed to release a secreted peptide termed endothelin 1. Thispeptide is a potent vasoconstrictor and is produced by vascularendothelial cells. Endothelin 1 also can affect the central nervoussystem. Two transcript variants encoding different isoforms havebeen found for this gene.
Gonsalves, C., et al. J. Immunol. 185(10):6253-6264(2010)Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) :Feng, J., et al. Circulation 122 (11 SUPPL), S150-S155 (2010) :Nikopensius, T., et al. Birth Defects Res. Part A Clin. Mol. Teratol. 88(9):748-756(2010)Kaparianos, A., et al. Eur Rev Med Pharmacol Sci 14(8):705-719(2010)
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