|Other Names||Transmembrane protein 204, Claudin-like protein 24, TMEM204, C16orf30, CLP24|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Can influence paracellular permeability. Appears to be involved in cell-cell interactions through adherens.|
|Cellular Location||Cell junction, adherens junction. Cell membrane; Multi-pass membrane protein. Note=Colocalizes with the beta- catenin adherins|
|Tissue Location||Highly expressed in lung, heart, kidney and placenta. Lower expression in thymus, spleen, liver, testis and ovary. Expressed in endothelial and restricted epithelial cell populations.|
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Provided below are standard protocols that you may find useful for product applications.
C16ORF30 plays a role in cell adhesion and cellularpermeability at adherens junctions (Kearsey et al., 2004 [PubMed15206924]).
Kearsey, J., et al. Eur. J. Biochem. 271(13):2584-2592(2004)Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)Kutsenko, A.S., et al. Nucleic Acids Res. 30(14):3163-3170(2002)Daniels, R.J., et al. Hum. Mol. Genet. 10(4):339-352(2001)
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