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FOLR4 Antibody (N-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | A6ND01 |
|---|---|
| Clone Names | 100309249 |
| Gene ID | 390243 |
|---|---|
| Other Names | Sperm-egg fusion protein Juno, Folate receptor 4, Folate receptor delta, FR-delta, IZUMO1 receptor protein JUNO, IZUMO1R (HGNC:32565), FOLR4, JUNO |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | IZUMO1R (HGNC:32565) |
|---|---|
| Function | Receptor for IZUMO1 present at the cell surface of oocytes (oolemma), which is essential for species-specific gamete recognition and fertilization. The IZUMO1:IZUMO1R/JUNO interaction is a necessary adhesion event between sperm and egg that is required for fertilization but is not sufficient for cell fusion. The ligand-receptor interaction probably does not act as a membrane 'fusogen'. Does not bind folate. |
| Cellular Location | Cell membrane {ECO:0000250|UniProtKB:Q9EQF4}; Lipid-anchor, GPI-anchor {ECO:0000250|UniProtKB:Q9EQF4}. Cell projection, microvillus membrane; Lipid- anchor, GPI-anchor {ECO:0000250|UniProtKB:Q9EQF4}. Note=GPI-anchored at the oolemma microvilli. {ECO:0000250|UniProtKB:Q9EQF4} |
| Tissue Location | Expressed in unfertilized oocytes (at protein level). |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Folate receptor 4 is a highly expressed cell surface marker of regulatory T cells.
References
Spiegelstein, O., et al. Gene 258 (1-2), 117-125 (2000) :
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