SAMC Blocking Peptide (Center)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q70HW3 |
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Other Accession | NP_775742.3 |
Gene ID | 115286 |
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Other Names | S-adenosylmethionine mitochondrial carrier protein, Mitochondrial S-adenosylmethionine transporter, Solute carrier family 25 member 26, SLC25A26, SAMC |
Target/Specificity | The synthetic peptide sequence is selected from aa 129-142 of HUMAN SLC25A26 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | SLC25A26 (HGNC:20661) |
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Function | Mitochondrial S-adenosyl-L-methionine/S-adenosyl-L- homocysteine antiporter. Mediates the exchange of cytosolic S-adenosyl- L-methionine, the predominant methyl-group donor for macromolecule methylation processes, for mitochondrial S-adenosylhomocysteine(SAH), a by-product of methylation reactions. |
Cellular Location | Mitochondrion inner membrane; Multi-pass membrane protein |
Tissue Location | Widely expressed. Highly expressed in testis, with moderate expression in brain, heart, kidney, lung, skeletal muscle, pancreas, small intestine and liver, and low expression in spleen |
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Provided below are standard protocols that you may find useful for product applications.
Background
Mitochondrial carriers, including SLC25A26, are a family of transport proteins found mostly in the inner membranes of mitochondria. They shuttle metabolites and cofactors through the mitochondrial membrane (Agrimi et al., 2004 [PubMed 14674884]).
References
Muzny, D.M., et al. Nature 440(7088):1194-1198(2006)
Agrimi, G., et al. Biochem. J. 379 (PT 1), 183-190 (2004) :
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