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DEPD5 Antibody (C-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession O75140
Clone Names 91208346
Peptide ID 91208346
Additional Information
Gene ID 9681
Other Names DEP domain-containing protein 5, DEPDC5, KIAA0645
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name DEPDC5
Synonyms KIAA0645
Function As a component of the GATOR1 complex functions as an inhibitor of the amino acid-sensing branch of the TORC1 pathway. The GATOR1 complex strongly increases GTP hydrolysis by RRAGA and RRAGB within RRAGC-containing heterodimers, thereby deactivating RRAGs, releasing mTORC1 from lysosomal surface and inhibiting mTORC1 signaling. The GATOR1 complex is negatively regulated by GATOR2 the other GATOR subcomplex in this amino acid-sensing branch of the TORC1 pathway.
Cellular Location Cytoplasm, cytosol. Cytoplasm, perinuclear region
Tissue Location Expressed in developing and adult brain.
Research Areas
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$ 80.00
Cat# BP12010b
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