|Other Accession||Q8WXH6, NP_001027004.1|
|Other Names||Ras-related protein Rab-40A-like, Ras-like GTPase, RAB40AL, RLGP|
|Target/Specificity||The synthetic peptide sequence is selected from aa 22-36 of HUMAN RAB40AL|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.|
|Cellular Location||Membrane; Lipid-anchor; Cytoplasmic side. Cytoplasm. Mitochondrion|
|Tissue Location||Expressed in brain, lung, heart, skeletal muscle, kidney and liver. Highest expression in brain. Expressed in fetal brain and kidney.|
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This gene encodes a member of the Rab40 subfamily of Rab small GTP-binding proteins that contains a C-terminal suppressors of cytokine signaling box. Disruptions in this gene are associated with Duchenne muscular dystrophy.
Saito-Ohara, F., et al. Am. J. Hum. Genet. 71(3):637-645(2002) Kile, B.T., et al. Trends Biochem. Sci. 27(5):235-241(2002)
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